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总部位于魁北克的 COVID-19 疫苗制造商 Medicago 将关闭 

2023-02-04 20:52:24
>>文章内容
Owner Mitsubishi Chemical Group blames decision on 'significant changes' to vaccine market
所有者三菱化学集团将这一决定归咎于疫苗市场的“重大变化”



CBC News · Posted: Feb 02, 2023 5:53 PM PST | Last Updated: February 2
CBC 新闻· 发布时间:2023 年 2 月 2 日下午 5:53 PST |最后更新:2 月 2 日


Quebec City-based vaccine maker Medicago Inc., is being shut down by owner Mitsubishi Chemical Group. (CBC)
总部位于魁北克市的疫苗制造商 Medicago Inc. 被所有者三菱化学集团关闭。 (CBC)

1023 comments


Mitsubishi Chemical Group is shutting down Medicago Inc., a COVID-19 vaccine manufacturer with headquarters in Quebec City.
三菱化学集团将关闭总部位于魁北克市的 COVID-19 疫苗制造商 Medicago Inc.。

A year ago, Medicago's plant-based COVID-19 vaccine, Covifenz, was approved by Health Canada, and it was touted as a homegrown shot against SARS-CoV-2.
一年前,Medicago 的基于植物的 COVID-19 疫苗 Covifenz 获得了加拿大卫生部的批准,并被吹捧为针对 SARS-CoV-2 的本土疫苗。

Then in March, the World Health Organization decided not to accept Medicago's COVID-19 vaccine for emergency use, citing the company's ties to big tobacco. Marlboro cigarette manufacturer Philip Morris International was once a shareholder of Medicago, but divested all of its shares in late 2022. 
然后在 3 月,世界卫生组织以该公司与大烟草的关系为由,决定不接受 Medicago 的 COVID-19 疫苗用于紧急使用。万宝路卷烟制造商菲利普莫里斯国际公司曾是 Medicago 的股东,但在 2022 年底剥离了其所有股份。

Medicago Inc., which was founded in 1997, is now 100 per cent owned by Mitsubishi Tanabe Pharma Corporation. 
Medicago Inc. 成立于 1997 年,现在由 Mitsubishi Tanabe Pharma Corporation 100% 拥有。

On Thursday, Medicago owner Mitsubishi Chemical Group issued a statement saying there have been "significant changes" to the vaccine market and, following a comprehensive analysis of the current global demand, the group decided to discontinue marketing Covifenz.
周四,Medicago 母公司三菱化学集团发表声明称,疫苗市场发生了“重大变化”,在对当前全球需求进行综合分析后,该集团决定停止销售 Covifenz。

"Furthermore, the group judged that it was not viable to continue to invest in the commercialization of Medicago's development products and therefore chose to terminate all its activities with Medicago and proceed with an orderly dissolution of its business affairs and activities," the statement said.
“此外,该集团认为继续投资于 Medicago 开发产品的商业化是不可行的,因此选择终止与 Medicago 的所有活动,并继续有序解散其业务和活动,”声明称。

The company's plant-based COVID-19 vaccine Covifenz was approved by Health Canada in 2022. (Turgut Yeter/CBC)
该公司基于植物的 COVID-19 疫苗 Covifenz 于 2022 年获得加拿大卫生部批准。(Turgut Yeter/CBC)

According to the statement, Medicago's business activities and regular operating activities will be significantly reduced and refocused during the liquidation process. 
根据声明,Medicago 的业务活动和常规经营活动将在清算过程中大幅减少和重新集中。

"Dissolution proceedings will take place in due course in accordance with local laws and regulations," it said.
“解散程序将根据当地法律法规在适当的时候进行,”它说。

Government invested $173M in Medicago
政府向 Medicago 投资了 1.73 亿美元


Canada's federal government invested $173 million into the company in 2020 to help the company develop the vaccine and its Quebec production facility. Ottawa also signed a deal to buy 20 million doses of the vaccine, with an option for 56 million more.
加拿大联邦政府在 2020 年向该公司投资了 1.73 亿美元,以帮助该公司开发疫苗及其在魁北克的生产设施。渥太华还签署了一项购买 2000 万剂疫苗的协议,并可选择再购买 5600 万剂。

The process developed by Medicago uses the plant species nicotiana benthamiana, a close relative of tobacco plants that is used for pharmaceutical development largely because of the high number of viruses that can successfully infect it. 
Medicago 开发的工艺使用植物本塞姆氏烟草,它是烟草植物的近亲,用于药物开发主要是因为大量病毒可以成功感染它。


When it was approved, studies of Covifenz found the two-dose shot's overall efficacy rate against all virus variants studied was 71 per cent, with a higher efficacy rate of 75 per cent against COVID-19 infections from the delta variant.
当它获得批准时,对 Covifenz 的研究发现,两剂疫苗对所研究的所有病毒变体的总体有效率为 71%,对来自 delta 变体的 COVID-19 感染的有效率更高,为 75%。

At the time, Health Canada said that "preliminary and exploratory data shows that Covifenz produces neutralizing antibodies against the Omicron variant."
当时,加拿大卫生部表示,“初步和探索性数据表明 Covifenz 产生了针对 Omicron 变体的中和抗体。”

On Twitter Thursday, Quebec City Mayor Bruno Marchand called the Medicago closure a "huge pity."
周四,魁北克市市长 Bruno Marchand 在推特上称 Medicago 的关闭是“巨大的遗憾”。

"My thoughts are with the families who learned some very sad news today," he said. "We have to roll up our sleeves to keep all this expertise in the field of health innovation in Quebec."
“我的想法与今天得知一些非常悲伤的消息的家庭在一起,”他说。 “我们必须挽起袖子,将所有这些专业知识留在魁北克的健康创新领域。”
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